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Ray, S., Tillo, D., Assad, N., Ufot, A., Deppmann, C., Durell, S.R., Porollo, A. and Vinson, C., 2018. Replacing C189 in the bZIP domain of Zta with S, T, V, or A changes DNA binding specificity to four types of double-stranded DNA. Biochemical and biophysical research communications501(4), pp.905-912.

Cheng, I., Jin, L., Rose, L.C. and Deppmann, C.D., 2018. Temporally restricted death and the role of p75 NTR as a survival receptor in the developing sensory nervous system. Developmental neurobiology.

Barford, K., Keeler, A., McMahon, L., McDaniel, K., Yap, C.C., Deppmann, C.D. and Winckler, B., 2018. Transcytosis of TrkA leads to diversification of dendritic signaling endosomes. Scientific reports8(1), p.4715.


Sipe, L. M., C. Yang, J. Ephrem, E. Garren, J. Hirsh, and C. D. Deppmann. "Differential sympathetic outflow to adipose depots is required for visceral fat loss in response to calorie restriction." Nutrition & diabetes 7, no. 4 (2017): e260.

Smith, C.J., Wheeler, M.A., Marjoram, L., Bagnat, M., Deppmann, C.D. and Kucenas, S., 2017. TNFa/TNFR2 signaling is required for glial ensheathment at the dorsal root entry zone. PLoS genetics13(4), p.e1006712.

Gamage, K.K., Cheng, I., Park, R.E., Karim, M.S., Edamura, K., Hughes, C., Spano, A.J., Erisir, A. and Deppmann, C.D. Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons. Current BiologyCurrent Biology (2017)


Wheeler MA, Smith CJ, Ottolini M, Barker BS, Purohit AM, Grippo RM, Gaykema RP, Spano AJ, Beenhakker MP, Kucenas S, Patel MK, Deppmann CD, Güler AD. Genetically targeted magnetic control of the nervous system. (2016) Nature Neuroscience

See Also: This article has been covered by 20 independent international news agencies including The Guardian, The Scientist, Daily Mail, Fox News and Arstechnica (as of March 25th, 2016).  Nature Reviews will be highlighting it in the upcoming issue. Online attention and activity reported by Altmetric scores this article in the 99th percentile compared to all other articles of the same age and is the 22nd out of roughly 3000 Nature neuroscience articles.  For more context see:


Suo, D., Park, J., Young, S., Makita, T., & Deppmann, C. D. (2015). Coronin-1 and Calcium Signaling Governs Sympathetic Final Target Innervation. The Journal of Neuroscience, 35(9), 3893-3902.  


Wheeler, M., Heffner, D., Kim, S., Espy S., Spano, A. Cleland, C., & Deppmann, CD (2014) TNFα/TNFR1 forward and reverse signaling is required for the development and function of primary nociceptors. Neuron 82(3):587-602. Link

See Also:  Science Signaling Editor's Choice: Dual Action Pain Modulator. Link

Sokolowski, J. D., Gamage, K. K., Heffron, D. S., LeBlanc, A. C., Deppmann, C. D., & Mandell, J. W. (2014). Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury. Acta neuropathologica communications2, 16. Link

Parameswaran, Nevi, Benjamin G. Dewals, Tom C. Giles, Christopher Deppmann, Martin Blythe, Alain Vanderplasschen, Richard D. Emes, and David Haig. "The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits." Virus research (2014). Link

Suo, D., Park, J., Harrington, A. W., Zweifel, L. S., Mihalas, S., & Deppmann, C. D. (2014). Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival. Nature neuroscience17(1), 36-45. PMID: 24270184


Vaccari, A., ^Gamage, K.K., #Nachum, S., Condron, B., Deppmann C.D., Acton, S.T., (2012) Image Analysis for Automated Assessment of Axon Degeneration. Asilomar Conf. on Signals, Systems and Computers. Link

Blasier, K.R., Mitchell, D.J., Ross,M.W., Smiley,W.R., ^Suo, D., #Park, J., Pullikuth, A.K., Catling, A.D., Deppmann, C.D., Pfister, K.K. Recruitment of dynein to endosomes for retrograde survival signal transport requires specific phosphorylation of the dynein intermediate chain by a Trk/ERK pathway. J. Neuroscience (2012) 32(44):15495-510 Link


 *Sharma N, *Deppmann C.D., *Harrington A.W., St Hillaire C., Chen Z.Y., Lee F.S., Ginty D.D. (2010) Long-Distance Control of Synapse Assembly by Target-Derived NGF. Neuron. 2010 Aug 12;67(3):422-34. Link

See Also:

  • Video Abstract

  • Newbern, J.M., Li, X., Snider, W.D. (2010) Signaling Endosomes Trigger Synapse Assembly.  Neuron.  Aug 12;67(3):352-4. Link

  • Faculty of 1000: evaluations for Sharma et al., Neuron (2010) Link 

  • Wong, Wei. "Synapse Specification Goes Retro." Science Signalling 3.135 (2010): ec248. Link

*Deppmann, C.D., *Mihalas, S., *Sharma, N., Lonze, B.E., Niebur, E, Ginty D.D. (2008) A Model for Neuronal Competition During Development. Science, 320(5874) 369-73.  Link

See Also:

  • Davies, A.M. (2008) Neurotrophins giveth and they taketh away. Nat. Neuro. 11(6):627-8. Link

  • Li, Y., Fivaz, M. (2008) Feedback-mediated neuronal competition for survival cues regulates innervation of a target tissue. Bioessays. 30(10):929-33 Link

  • Faculty of 1000 Medicine: evaluations for Deppmann CD et al Science 2008 Apr 18 320 (5874) :369-73

Deppmann, C.D., Alvania, R.A., Taparowsky, E.J. (2006) Cross-species Annotation of Basic Leucine Zipper Factor Interactions: Insight Into the Evolution of Closed Interaction Networks. Mol. Biol. Evol. 23(8), 1480-92. Link

Deppmann, C.D., Acharya, A., Rishi, V., Wobbes, B., Smeekens, S., Taparowsky, E.J., Vinson, C. (2004). Dimerization Specificity of All 67 B-ZIP Motifs in Arabidopsis thaliana: A Comparison to Homo sapiens B-ZIP Motifs. Nuc. Acids Res. 32(11), 3435-45. Link

Deppmann, C.D., Thornton T.M., Utama, F.E., Taparowsky, E.J. (2003). Phosphorylation of BATF Regulates DNA binding: a Novel Mechanism for AP-1 (Activator Protein-1) Regulation. Biochem J. 374(Pt 2), 423-31.   Link

Johansen L.M., Deppmann, C.D., Erickson K.D., Coffin W.F. 3rd, Thornton T.M., Humphrey S.E., Martin, J.M. Taparowsky, E.J. (2003). BATF is a Cellular Target of the Epstein-Barr Virus Transactivator Protein, EBNA-2. J. Virol. 77, 6029-40.  Link

Williams K.L., Zullo, A.J., Kaplan, M.H., Brutkiewicz, R.R., Deppmann, C.D., Vinson C, Taparowsky, E.J. (2003). BATF Transgenic Mice Reveal a Role for AP-1 in NKT Cell Development. J. Immunol. 170, 2417-26.  Link

Deppmann, C.D., Taparowsky, E.J. (2003). Reverse-polarity PAGE for examining DNA binding domain phosphorylation. Biotechniques. 34, 56-9.

Book Chapters and Reviews:


McGirr, B.*, Tubergen, P*, Hartz, J., Myers, P., Pittman, M., Lazzara, M., Deppmann, C. A Process Controls Approach to Cell Signaling, Encyclopedia of Life Sciences.Invited review (2018) PMCID: NA

McMullen, T.*, Brown, E*, Ausrafuggaman, N., Sahu, A., Guler, A., Deppmann, C.GPCR signal transduction: Evolution by gene duplication, Encyclopedia of Life Sciences.Invited review, (2018) PMCID: NA


Barford K, Keeler A, Deppmann C, Winckler B. TrkA Bumps into Its Future Self. Dev Cell. 2017 Sep 25;42(6):557–558. PMID: 28950095

Barford K, Deppmann C, Winckler B. The neurotrophin receptor signaling endosome: Where trafficking meets signaling. Dev Neurobiol. 2017 Feb 24;77(4):405–418. PMCID: PMC5661883

Yong, Yu, Heckle, Lindsay A, Arena, Kimberly A, Goertz, Jennifer E, Kucenas, Sarah, and Deppmann, Christopher D(Aug 2017) Glia Signalling during Neurological Damage and Disease. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0027501] PMCID: NA

Guessoum, Omar, Tang, Qijun, Agorsor, Israel DK, Ke, Wenfan, Li, Renyu, Danna, Cristian H, and Deppmann, Christopher D(Aug 2017) TLR Signalling: Beyond Immunity. In: eLS. John Wiley & Sons Ltd, Chichester. [doi: 10.1002/9780470015902.a0027502] PMCID: NA

Keeler AB, Deppmann CD. The evolutionary origins of antagonistic neurotrophin signaling. J Cell Biol. 2017 May 1;216(5):1223–1225. PMCID: PMC5412573

Martorella M, Barford K, Winkler B, Deppmann CD. Emergent Role of Coronin-1a in Neuronal Signaling. Vitam Horm. 2017;104:113–131. PMCID: PMC5667946


Ross, EF Ali, MF, Woo, LA, Chadwick, SR Lee, E. Sangston, RM, Sood, C, Zhang, Q Zhang, X, +Deppmann, CD(2016) Reverse Signaling Encyclopedia of Life SciencesPMCID: NA


Huckaby A, Dombrovski M, Maher E, Naimi W, Perez M, Skyberg R, Smolko C, Barford K, Winckler B, +Deppmann CD. (November 2015) Signaling from endosomes and exosomes. Encyclopedia of Life Sciences. PMCID: NA


*^Pahl, M, *^Askinazi, O., *^Hamilton, M., ^Cheng, I., ^Kuhn, J., ^Cichewicz, K., +Deppmann, C.D. (2013) Signaling via single-pass transmembrane receptors. Encyclopedia of Life Sciences.  Link

+Deppmann, C.D., and +Janes K. (2013) Cytokine-cytokine crosstalk and cell-death decisions. Systems Biology of Apopotosis. Springer publishers. Systems Biology of Apoptosis : 163-180. Link


 *^Kodis, E., *^Smindek, R., *^Kefauver, J., *Heffner, D., ^Aschenbach, K., Brennan, E., #Chan, K., ^Gamage, K.K., #Lambeth, P., Lawler, J., ^Sikora, A., #Vercroysse, N., +Deppmann C.D. First Messengers. Encyclopedia of Life Sciences. (2012) Link


Deppmann, C.D., Ginty D.D. (2006) Retrograde Control of Neural Circuit Formation. Cell 127(7) 1306-7. Link

  • + Corresponding Author

  • *equal contribution

  • #UVA Undergrad Student

  • ^UVA Grad student